#GeneName	Shortname	Role	DonorNode	DNtime	ReceptorNode	RNtime	MSMH_OUT	MSMH_IN	AI(CHE)	hU(CHS)	hBL(CHBL)	NodeLevel	OG1157Term	EGGNOGTerm	PANTHERTerm	SuperFamilyTerm	InterproscanTerm	GOTerm	KEGGTerm	PfamTerm	KO
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_096644070.1@@2692894	WP_096644070.1	asReceptor	Bacteria.Proteobacteria.Proteobacteria	2910	Bacteria.Cyanobacteria.Cyanobacteria	2245	Bacteria--Proteobacteria--Rhodocyclaceae_bacterium.WP_102040513.1@@1898103	Bacteria--Terrabacteria--Nostoc_sp._CENA543.WP_103136486.1@@1869241,Bacteria--Terrabacteria--Chroococcales_cyanobacterium_IPPAS_B-1203.WP_099699409.1@@2049454	64.92(100.0)	163.7(100.0)	1.75(100.0)	1	OG.7577	COG0783	PTHR42932	SSF47240	IPR002177|IPR009078	-	NA	ko00000,ko03036	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_096645755.1@@2692894	WP_096645755.1	asDonor	Bacteria.Cyanobacteria.Cyanobacteria	2245	Archaea.Crenarchaeota.Desulfurococcales	1518	Bacteria--Terrabacteria--Nostoc_sp._CENA543.WP_103138894.1@@1869241	Archaea.Crenarchaeota--Thermopro--Hyperthermus_butylicus.WP_011821779.1@@54248,Archaea.Crenarchaeota--Thermopro--Staphylothermus_marinus.WP_011839763.1@@2280,Archaea.Crenarchaeota--Thermopro--Staphylothermus_hellenicus.WP_013143268.1@@84599	75.61(100.0)	229.0(100.0)	99.82(100.0)	1	NA	NA	NA	NA	NA	-	NA	-	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_190549127.1@@2692894	WP_190549127.1	asDonor	Bacteria.Cyanobacteria.Cyanobacteria	2245	Archaea.Euryarchaeota.Methanobacterium	146	Bacteria--Terrabacteria--Chroococcales_cyanobacterium_IPPAS_B-1203.WP_099702835.1@@2049454	Archaea.Euryarchaeota--Methanoba--Methanobacterium_formicicum.WP_004031973.1@@2162,Archaea.Euryarchaeota--Methanoba--Methanobacterium_lacus.WP_013644992.1@@877455	74.21(100.0)	223.0(100.0)	99.53(100.0)	1	NA	NA	NA	NA	NA	-	NA	ko00000,ko01000	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_190547002.1@@2692894	WP_190547002.1	asReceptor	Bacteria.Proteobacteria.Alphaproteobacteria	2480	Bacteria.Cyanobacteria.Cyanobacteria	2245	Bacteria.Alphaproteobacteria--NA--Rhizobium_sp..WP_084368515.1@@2364272	Bacteria--Terrabacteria--Hydrococcus_rivularis.WP_073598817.1@@1616834	121.84(100.0)	363.0(100.0)	99.03(100.0)	1	OG.2482	COG0399	PTHR30244	SSF53383	IPR015424|IPR000653	-	NA	-	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_190539492.1@@2692894	WP_190539492.1	asDonor	Bacteria.Cyanobacteria.Cyanobacteria	2245	Archaea.Euryarchaeota.Halobacteria	455	Bacteria--Terrabacteria--filamentous_cyanobacterium_Phorm_6.WP_106148374.1@@2107706	Archaea--Euryarchaeota--Haloprofundus_sp._MHR1.WP_137049092.1@@2572921,Archaea--Euryarchaeota--Saliphagus_sp._LR7.WP_114579335.1@@2282654,Archaea.Euryarchaeota--Halobacte--Halogranum_salarium.WP_009732969.1@@693851,Archaea.Euryarchaeota--Halobacte--Halorubrum_lacusprofundi.WP_015910638.1@@2247,Archaea.Euryarchaeota--Halobacte--Haloarcula_rubripromontorii.WP_053967444.1@@1705562,Archaea.Euryarchaeota--Halobacte--Halorubrum_sp..WP_017342724.1@@2497325,Archaea.Euryarchaeota--Halobacte--Haloferax_mucosum.WP_049915356.1@@403181,Archaea.Euryarchaeota--Halobacte--Haloferax_gibbonsii.WP_050459314.1@@35746,Archaea.Euryarchaeota--Halobacte--Natrinema_versiforme.WP_006430965.1@@88724,Archaea--Euryarchaeota--Halostella_sp._DLLS-108.WP_135821029.1@@2528831,Archaea.Euryarchaeota--Halobacte--Candidatus_Halobonum.WP_023394961.1@@1431544,Archaea.Euryarchaeota--Halobacte--Haloterrigena_salina.WP_008894898.1@@504937,Archaea--Euryarchaeota--Haloprofundus_sp._MHR1.WP_137047036.1@@2572921,Archaea.Euryarchaeota--Halobacte--Natrinema_pallidum.WP_006185663.1@@69527	43.6(100.0)	138.0(100.0)	99.58(100.0)	1	OG.11492	arCOG10153	PTHR35519	NA	IPR025187	-	NA	-	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_190546286.1@@2692894	WP_190546286.1	asDonor	Bacteria.Cyanobacteria.Cyanobacteria	2245	Eukaryota.Viridiplantae.Streptophyta.Pentapetalae	117	Bacteria--Terrabacteria--Nostoc_sp._CENA543.WP_103135570.1@@1869241	Viridiplantae--Tracheophyta--Cucurpe.XP_023541126.1@@3663,Viridiplantae--Tracheophyta--Cucurpe.XP_023545672.1@@3663,Viridiplantae--Tracheophyta--Cucurpe.XP_023517551.1@@3663,Viridiplantae--Tracheophyta--Oleaeu.XP_022895671.1@@4146,Viridiplantae--Tracheophyta--Cucurpe.XP_023547622.1@@3663	33.17(100.0)	79.5(100.0)	1.14(100.0)	1	OG.1810	COG0694	PTHR11178:SF39	SSF117916	IPR034904	-	NA	-	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_242046124.1@@2692894	WP_242046124.1	asDonor	Bacteria.Cyanobacteria.Cyanobacteria	2245	Archaea.Euryarchaeota.Methanobacteriaceae	345	Bacteria--Terrabacteria--Nostoc_sp._CENA543.WP_103135816.1@@1869241	Archaea.Euryarchaeota--Methanoba--Methanobacterium.WP_048082554.1@@2160,Archaea--Euryarchaeota--Methanobacterium_sp._MZ-A1.WP_100906257.1@@1911685,Archaea.Euryarchaeota--Methanoba--Methanothermobacter_sp..WP_048176291.1@@1884223,Archaea--Euryarchaeota--Methanobacterium_sp._MZ-A1.WP_100905556.1@@1911685,Archaea.Euryarchaeota--Methanoba--Methanobacterium_formicicum.WP_048072531.1@@2162,Archaea.Euryarchaeota--Methanoba--Methanobacterium.WP_048081928.1@@2160,Archaea.Euryarchaeota--Methanoba--Methanobacterium_formicicum.WP_048073454.1@@2162,Archaea--Euryarchaeota--Methanobacterium_sp._MZ-A1.WP_100906576.1@@1911685,Archaea.Euryarchaeota--Methanoba--Methanobacterium.WP_052376197.1@@2160,Archaea.Euryarchaeota--Methanoba--Methanobacterium.WP_048081929.1@@2160,Archaea.Euryarchaeota--Methanoba--Methanobacterium_formicicum.WP_048072532.1@@2162,Archaea.Euryarchaeota--Methanoba--Methanobacterium_formicicum.WP_048072900.1@@2162,Archaea--Euryarchaeota--Methanobacterium_sp._MZ-A1.WP_100907233.1@@1911685,Archaea--Euryarchaeota--Methanobacterium_sp._MZ-A1.WP_100907234.1@@1911685,Archaea.Euryarchaeota--Methanoba--Methanobacterium_formicicum.WP_048072901.1@@2162,Archaea--Euryarchaeota--Methanobacterium_sp._MZ-A1.WP_100905555.1@@1911685,Archaea.Euryarchaeota--Methanoba--Methanobacterium_formicicum.WP_048072416.1@@2162,Archaea.Euryarchaeota--Methanoba--Methanothermobacter.WP_010876086.1@@145260,Archaea.Euryarchaeota--Methanoba--Methanobacterium.WP_048080042.1@@2160,Archaea.Euryarchaeota--Methanoba--Methanothermobacter_sp..WP_048175565.1@@1884223,Archaea.Euryarchaeota--Methanoba--Methanothermobacter_sp..WP_052457309.1@@1884223	22.52(100.0)	61.9(100.0)	2.32(100.0)	1	OG.192	arCOG02349	PTHR43228	SSF52172	IPR011006	-	NA	-	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_190542300.1@@2692894	WP_190542300.1	asDonor	Bacteria.Cyanobacteria.Cyanobacteria	2245	Eukaryota.Viridiplantae.Streptophyta.Pentapetalae	117	Bacteria--Terrabacteria--Chroococcales_cyanobacterium_IPPAS_B-1203.WP_099700561.1@@2049454	Viridiplantae--Tracheophyta--Cucurpe.XP_023542757.1@@3663,Viridiplantae--Tracheophyta--Cucurpe.XP_023519056.1@@3663,Viridiplantae--Tracheophyta--Cucurpe.XP_023514764.1@@3663,Viridiplantae--Tracheophyta--Oleaeu.XP_022891926.1@@4146	26.04(100.0)	66.0(100.0)	0.4(100.0)	1	OG.245	COG0105	PTHR11349:SF44	SSF54919	IPR036850	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360	MetaCyc: PWY-7222|MetaCyc: PWY-7221|MetaCyc: PWY-7184|KEGG: 00230+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7227|MetaCyc: PWY-7220|MetaCyc: PWY-7224|KEGG: 00983+2.7.4.6|MetaCyc: PWY-7205|MetaCyc: PWY-7226|KEGG: 00240+2.7.4.6|MetaCyc: PWY-7210|MetaCyc: PWY-7198|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7176	ko00000,ko00001,ko00002,ko01000,ko04131	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_190541850.1@@2692894	WP_190541850.1	asDonor	Bacteria.Terrabacteria_group	3190	Bacteria.Proteobacteria.Gammaproteobacteria	2480	Bacteria--Terrabacteria--Acaryochloris_marina.WP_049783673.1@@155978	Bacteria--Proteobacteria--Hahella_sp._KA22.WP_127974309.1@@1628392,Bacteria--Proteobacteria--Gallaecimonas_sp._HK-28.WP_115720622.1@@2291597	58.39(100.0)	182.0(100.0)	99.56(100.0)	1	OG.11183	COG1397	NA	NA	NA	-	NA	-	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_096643308.1@@2692894	WP_096643308.1	asDonor	Bacteria.Terrabacteria_group	3190	Bacteria.Actinobacteria.Acidimicrobiales	281	Bacteria--Terrabacteria--Chroococcales_cyanobacterium_IPPAS_B-1203.WP_099701409.1@@2049454	Bacteria.Actinobacteria--Acidimicr--Ilumatobacter_coccineus.WP_015440401.1@@467094,Bacteria.Actinobacteria--Acidimicr--Acidimicrobium_ferrooxidans.WP_015797882.1@@53635,Bacteria.Actinobacteria--Acidimicr--Candidatus_Microthrix.WP_020379232.1@@41949,Bacteria.Actinobacteria--Acidimicr--Ferrithrix_thermotolerans.WP_072788165.1@@209649,Bacteria.Actinobacteria--Acidimicr--Ferrimicrobium_acidiphilum.WP_035389055.1@@121039	102.24(100.0)	291.0(100.0)	99.79(100.0)	1	NA	NA	NA	NA	NA	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	NA	br01610,ko00000,ko00001,ko00002,ko03011	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_190545860.1@@2692894	WP_190545860.1	asDonor	Bacteria.Terrabacteria_group	3190	Bacteria.Firmicutes.Bacillales	2030	Bacteria--Terrabacteria--Capsulimonas_corticalis.WP_125206249.1@@2219043	Bacteria.Firmicutes--Bacilli--Paenibacillus_daejeonensis.WP_020620884.1@@135193,Bacteria.Firmicutes--Bacilli--Paenibacillus_sp..WP_079913214.1@@2509456,Bacteria.Firmicutes--Bacilli--Paenibacillus_algorifonticola.WP_052737158.1@@684063,Bacteria.Firmicutes--Bacilli--Paenibacillus_ferrarius.WP_079408831.1@@1469647,Bacteria.Firmicutes--Bacilli--Brevibacillus_formosus.WP_052773408.1@@54913,Bacteria.Firmicutes--Bacilli--Paenibacillus_sp..WP_051478046.1@@2509456,Bacteria.Firmicutes--Bacilli--Paenibacillus_jamilae.WP_063212535.1@@114136,Bacteria.Firmicutes--Bacilli--Brevibacillus_formosus.WP_047072924.1@@54913,Bacteria.Firmicutes--Bacilli--Paenibacillus_fonticola.WP_019637121.1@@379896,Bacteria.Firmicutes--Bacilli--Lysinibacillus_fusiformis.WP_052059878.1@@28031,Bacteria.Firmicutes--Bacilli--Paenibacillus_dauci.WP_052714232.1@@1567106,Bacteria.Firmicutes--Bacilli--Lysinibacillus_sphaericus.WP_031417360.1@@1421,Bacteria.Firmicutes--Bacilli--Paenibacillus_sp..WP_052421400.1@@2509456,Bacteria.Firmicutes--Bacilli--Paenibacillus_algorifonticola.WP_052737407.1@@684063,Bacteria.Firmicutes--Bacilli--Paenibacillus_mucilaginosus.WP_014652372.1@@61624	6.1(100.0)	16.0(100.0)	0.08(100.0)	1	NA	NA	NA	NA	NA	NA	NA	NA	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_190539635.1@@2692894	WP_190539635.1	asDonor	Bacteria.Cyanobacteria.Cyanobacteria	2245	Bacteria.Acidobacteria.Acidobacteriaceae	488	Bacteria--Terrabacteria--Chroococcales_cyanobacterium_IPPAS_B-1203.WP_099702894.1@@2049454	Bacteria.Acidobacteria--Acidobact--Granulicella_tundricola.WP_013579435.1@@940615,Bacteria.Acidobacteria--Acidobact--Terriglobus_saanensis.WP_013567212.1@@870903,Bacteria.Acidobacteria--Acidobact--Acidobacteriaceae_bacterium.WP_020706810.1@@2052142,Bacteria.Acidobacteria--Acidobact--Terriglobus_roseus.WP_014787306.1@@392734,Bacteria.Acidobacteria--Acidobact--Acidobacteriaceae_bacterium.WP_022844256.1@@2052142,Bacteria.Acidobacteria--Acidobact--Acidobacteriaceae_bacterium.WP_020714650.1@@2052142,Bacteria.Acidobacteria--Acidobact--Acidobacterium_capsulatum.WP_015896854.1@@33075,Bacteria.Acidobacteria--Acidobact--Candidatus_Koribacter.WP_011524304.1@@658061	13.29(100.0)	33.9(100.0)	1.42(100.0)	1	NA	NA	NA	NA	NA	-	NA	-	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_190548586.1@@2692894	WP_190548586.1	asReceptor	Bacteria.Firmicutes.Firmicutes	2620	Bacteria.Cyanobacteria.Cyanobacteria	2245	Bacteria.Firmicutes--Bacilli--Aneurinibacillus_tyrosinisolvens.WP_047154585.1@@1443435	Bacteria--Terrabacteria--Leptolyngbya_sp._NIES-3755.WP_068382202.1@@1752064,Bacteria--Terrabacteria--Chlorogloea_sp._CCALA_695.WP_106371363.1@@2107693	21.9(100.0)	92.0(100.0)	99.27(100.0)	1	OG.6613	COG1061	PTHR11274:SF14	SSF52540	IPR027417	GO:0016787|GO:0004519|GO:0003677|GO:0005524|GO:0003676	NA	PF04851|PF00271|PF01844	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_190542329.1@@2692894	WP_190542329.1	asDonor	Bacteria.Terrabacteria_group	3190	Bacteria.Bacteroidetes.Chitinophagaceae	403	Bacteria--Terrabacteria--Chlorogloea_sp._CCALA_695.WP_106371382.1@@2107693	Bacteria.Bacteroidetes--Chitinoph--Segetibacter_koreensis.WP_018616103.1@@398037,Bacteria.Bacteroidetes--Chitinoph--Niastella_vici.WP_081153362.1@@1703345,Bacteria.Bacteroidetes--Chitinoph--Niastella_populi.WP_081169254.1@@550983,Bacteria.Bacteroidetes--Chitinoph--Niastella_koreensis.WP_049815680.1@@354356,Bacteria.Bacteroidetes--Chitinoph--Flavihumibacter_sp..WP_052323832.1@@1913981,Bacteria.Bacteroidetes--Chitinoph--Chitinophaga_ginsengisegetis.WP_079470338.1@@393003,Bacteria.Bacteroidetes--Chitinoph--Chitinophaga_eiseniae.WP_078667393.1@@634771	69.98(100.0)	214.0(100.0)	99.43(100.0)	1	NA	NA	NA	NA	NA	-	NA	ko00000,ko00001,ko01000	NA
Cyanobacteria--Cyanobacteria--Calothrix_anomala_FACHB-343.WP_190540356.1@@2692894	WP_190540356.1	asReceptor	Archaea.Archaea	4147	Bacteria.Cyanobacteria.Cyanobacteria	2245	Archaea--Euryarchaeota--Methanoculleus_sp._MAB1.WP_014866775.1@@86622	Bacteria--Terrabacteria--Chroococcales_cyanobacterium_IPPAS_B-1203.WP_099701626.1@@2049454	58.61(100.0)	148.8(100.0)	1.72(100.0)	1	OG.1222	COG0590	PTHR11079	SSF53927	IPR016193	-	Reactome: R-HSA-6782315	ko00000,ko00001,ko01000	NA